Across TCGA cell cohorts, CYHR1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CYHR1-associated genes across cancer lineages are SLC5A5, WNT3A, and TAFA1. Each is linked with CYHR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYHR1-to-partner and partner-to-CYHR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYHR1→partner) and Y-score (partner→CYHR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC5A5 →	+0.282	+2.716	<.001	.009	3	1
LARGE_INTESTINE	WNT3A →	+0.311	+3.464	<.001	.004	3	1
LARGE_INTESTINE	TAFA1 →	+0.205	+2.688	.004	.008	3	1
LARGE_INTESTINE	CHSY3 →	+0.574	+3.474	<.001	.003	3	1
BLOOD_Leukemia	PRR30 →	+0.015	+3.269	<.001	.007	3	1
BLOOD_Leukemia	IQCF5 →	+0.061	+3.786	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

CYHR1 survival (RNA) · tumor vs normal (RNA) · all CYHR1 data types