CYGB

Across TCGA patient cohorts, CYGB protein abundance is significantly associated with the RNA expression of many other genes, with 16,283 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CYGB-associated genes across cancer lineages are FHL5, LRRC32, and RCAN2. Each is linked with CYGB in more than 9 cancer types. Because this analysis shows association rather than direction, both CYGB-to-partner and partner-to-CYGB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYGB versus FHL5 in PDAC, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYGB→partner) and Y-score (partner→CYGB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	FHL5 →	+1.087	+0.474	<.001	<.001	3	10
COAD	LRRC32 →	+0.876	+0.263	.001	.001	3	10
GBM	RCAN2 →	+1.926	+0.549	<.001	<.001	3	10
OV	CPED1 →	+0.950	+0.632	<.001	.003	3	9
OV	SEPTIN4 →	+0.650	+0.706	<.001	<.001	3	9
OV	C7 →	+1.964	+0.642	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,283 associations by consensus.

CYGB vs FHL5 — PDAC

Explore this scatter interactively →