CYGB

Across TCGA cell cohorts, CYGB RNA expression is significantly associated with the go_rna of many other GO terms, with 2,396 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CYGB-associated GO terms across cancer lineages are Response to endoplasmic reticulum stress, Response to acid chemical, and Response to amino acid. Each is linked with CYGB in more than 8 cancer types. Because this analysis shows association rather than direction, both CYGB-to-partner and partner-to-CYGB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to endoplasmic reticulum stress grouped by CYGB-low versus CYGB-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYGB→partner) and Y-score (partner→CYGB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Response to endoplasmic reticulum stress →	+0.055	+0.428	.002	.004	3	9
OVARY	Response to acid chemical →	+0.070	+1.654	<.001	<.001	3	9
SKIN	Response to amino acid →	+0.061	+3.087	<.001	.001	3	8
OESOPHAGUS	Positive regulation of Wnt signaling pathway →	+0.044	+0.397	.002	.001	2	8
BLOOD_Myeloma	Lipid storage →	+0.088	+0.257	<.001	.009	3	7
BREAST	Endoderm development →	+0.105	+0.620	<.001	.006	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,396 associations by consensus.

Response to endoplasmic reticulum stress by CYGB expression — STOMACH

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