CYFIP1

Across TCGA patient cohorts, CYFIP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,533 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CYFIP1-associated proteins across cancer lineages are PRDX4, NARS2, and TBC1D2B. Each is linked with CYFIP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CYFIP1-to-partner and partner-to-CYFIP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYFIP1 versus PRDX4 in CCRCC, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYFIP1→partner) and Y-score (partner→CYFIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PRDX4 →	-0.362	-0.230	.006	.007	3	5
OV	NARS2 →	-0.549	-0.499	.001	.002	3	5
GBM	TBC1D2B →	+0.239	+0.391	<.001	<.001	3	5
PDAC	PYCR2 →	-0.486	-0.391	<.001	<.001	3	4
GBM	VPS18 →	+0.146	+0.431	.005	<.001	3	4
GBM	MRC1 →	+0.688	+0.269	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,533 associations by consensus.

CYFIP1 vs PRDX4 — CCRCC

Explore this scatter interactively →