CYFIP1

Across TCGA patient cohorts, CYFIP1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,760 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CYFIP1-associated genes across cancer lineages are ABI1, TMBIM1, and DGKA. Each is linked with CYFIP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CYFIP1-to-partner and partner-to-CYFIP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYFIP1 versus ABI1 in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYFIP1→partner) and Y-score (partner→CYFIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ABI1 →	+0.665	+0.169	<.001	<.001	3	6
HNSC	TMBIM1 →	+0.677	+0.140	<.001	<.001	3	4
LUAD	DGKA →	+0.444	+0.127	<.001	<.001	3	4
BRCA	SPTBN4 →	-0.466	-0.136	.003	<.001	3	4
HNSC	SCML2 →	-0.837	-0.235	.001	<.001	3	3
GBM	TNFSF13B →	+0.600	+0.198	.006	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,760 associations by consensus.

CYFIP1 vs ABI1 — HNSC

Explore this scatter interactively →