CYCSP8

Across TCGA pan-cancer cohorts, CYCSP8 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated CYCSP8 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CYCSP8 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CYCSP8 expression acts as an unfavorable survival marker, although some lineages such as LGG and PAAD show a favorable association.

KIRC, STAD, and LGG are the cancer types where CYCSP8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.695	0.880	.004	108	view →
STAD	OS	Tertile	II,III,IV	0.462	0.758	<.001	54	view →
LGG	DFS	Median	All	0.479	0.328	<.001	50	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
ESCA	OS	Tertile	II,III,IV	0.105	0.867	.016	30	view →
BRCA	DFS	Tertile	All	0.236	0.534	.002	30	view →
OV	OS	Tertile	II,III,IV	0.712	0.847	.017	30	view →
BLCA	OS	Tertile	IV	0.153	0.599	.018	27	view →
READ	DFS	Tertile	All	0.162	0.720	.019	27	view →
SKCM	OS	Tertile	All	0.115	0.326	.005	24	view →
ACC	DFS	Tertile	II,III,IV	0.242	0.724	.034	18	view →
PRAD	OS	Tertile	All	0.958	0.995	.016	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

CYCSP8–KIRC (OS)

Open the KIRC breakdown →