CYCSP44

Across TCGA pan-cancer cohorts, CYCSP44 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated CYCSP44 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher CYCSP44 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CYCSP44 expression acts as an unfavorable survival marker, although some lineages such as COAD and HNSC show a favorable association.

CESC, ACC, and COAD are the cancer types where CYCSP44 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Tertile	IV	0.348	0.638	.006	66	view →
ACC	OS	Tertile	II,III,IV	0.599	0.891	.001	36	view →
COAD	DFS	Tertile	All	0.809	0.660	.016	21	view →
KIRC	DFS	Tertile	IV	0.235	0.512	.036	18	view →
HNSC	OS	Tertile	All	0.813	0.557	.014	15	view →
UCS	OS	Tertile	IV	0.844	0.244	.019	12	view →
UCEC	OS	Tertile	All	0.335	0.716	.009	12	view →
SKCM	DFS	Tertile	IV	0.134	0.589	.031	9	view →
LUAD	OS	Tertile	All	0.738	0.825	.046	3	view →
LIHC	OS	Tertile	All	0.948	0.743	.040	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

CYCSP44–CESC (OS)

Open the CESC breakdown →