CYCSP41

Across TCGA pan-cancer cohorts, CYCSP41 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated CYCSP41 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher CYCSP41 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CYCSP41 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

LIHC, HNSC, and COAD are the cancer types where CYCSP41 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	II,III,IV	0.261	0.639	<.001	102	view →
HNSC	DFS	Tertile	All	0.873	0.680	.003	81	view →
COAD	DFS	Tertile	All	0.167	0.794	<.001	72	view →
STAD	DFS	Tertile	All	0.550	0.689	.006	46	view →
LUAD	DFS	Tertile	III,IV	0.610	0.261	.022	33	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	27	view →
UCS	DFS	Tertile	III,IV	0.618	0.181	.027	24	view →
SKCM	OS	Tertile	All	0.847	0.763	.012	18	view →
CESC	DFS	Tertile	II,III,IV	0.146	0.705	.010	18	view →
PCPG	DFS	Tertile	All	0.051	0.773	<.001	18	view →
LGG	DFS	Tertile	All	0.280	0.757	.002	18	view →
SARC	OS	Tertile	All	0.176	0.520	.038	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

CYCSP41–LIHC (OS)

Open the LIHC breakdown →