CYCSP40

Across TCGA patient cohorts, CYCSP40 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,682 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CYCSP40-associated proteins across cancer lineages are PEAR1_S1029, ASAP1_S1008, and RIOK2_S337. Each is linked with CYCSP40 in more than 4 cancer types. Because this analysis shows association rather than direction, both CYCSP40-to-partner and partner-to-CYCSP40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYCSP40 versus PEAR1_S1029 in PDAC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYCSP40→partner) and Y-score (partner→CYCSP40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PEAR1_S1029 →	+0.453	+0.587	<.001	<.001	3	5
CCRCC	ASAP1_S1008 →	+0.511	+0.643	<.001	<.001	3	5
GBM	RIOK2_S337 →	-0.391	-0.684	.003	.002	3	3
GBM	SET_S7 →	+0.482	+0.561	<.001	.002	3	3
CCRCC	CD34 →	+0.773	+0.875	<.001	<.001	3	3
CCRCC	CD93 →	+0.551	+0.527	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,682 associations by consensus.

CYCSP40 vs PEAR1_S1029 — PDAC

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