CYCSP35

Across TCGA patient cohorts, CYCSP35 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,338 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CYCSP35-associated GO terms across cancer lineages are Methylation, Regulation of post-translational protein modification, and Regulation of ubiquitin-dependent protein catabolic process. Each is linked with CYCSP35 in more than 11 cancer types. Because this analysis shows association rather than direction, both CYCSP35-to-partner and partner-to-CYCSP35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Methylation grouped by CYCSP35-low versus CYCSP35-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYCSP35→partner) and Y-score (partner→CYCSP35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Methylation →	+0.052	+0.443	<.001	<.001	3	12
ESCA	Regulation of post-translational protein modification →	+0.068	+0.327	<.001	<.001	3	11
ESCA	Regulation of ubiquitin-dependent protein catabolic process →	+0.065	+0.330	<.001	<.001	3	11
STAD	Nucleoside triphosphate biosynthetic process →	+0.067	+0.401	<.001	<.001	3	11
ESCA	Regulation of protein ubiquitination →	+0.068	+0.340	<.001	<.001	3	11
STAD	Peptidyl-lysine modification →	+0.054	+0.394	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,338 associations by consensus.

Methylation by CYCSP35 expression — STAD

Explore this box plot interactively →