CYCSP29

Across TCGA pan-cancer cohorts, CYCSP29 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated CYCSP29 data layer.

The strongest signal is observed in thymoma (THYM), where higher CYCSP29 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CYCSP29 expression acts as an unfavorable survival marker, although some lineages such as PAAD show a favorable association.

THYM, ACC, and MESO are the cancer types where CYCSP29 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	DFS	Tertile	All	0.521	0.946	<.001	87	view →
ACC	OS	Tertile	All	0.133	0.686	.004	36	view →
MESO	OS	Tertile	III,IV	0.262	0.602	.003	27	view →
KIRC	DFS	Tertile	All	0.315	0.659	.006	21	view →
DLBC	DFS	Tertile	III,IV	0.137	0.790	<.001	18	view →
OV	DFS	Tertile	IV	0.310	0.487	.037	18	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	12	view →
ESCA	OS	Median	All	0.387	1.000	.003	12	view →
READ	DFS	Tertile	III,IV	0.082	0.760	.001	9	view →
PAAD	OS	Tertile	II,III,IV	0.653	0.344	.035	3	view →
HNSC	OS	Tertile	III,IV	0.606	0.751	.046	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

CYCSP29–THYM (DFS)

Open the THYM breakdown →