CYCSP28

Across TCGA pan-cancer cohorts, CYCSP28 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CYCSP28’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where CYCSP28 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CYCSP28 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

STAD, KICH, and HNSC are the cancer types where CYCSP28 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CYCSP28 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	II,III,IV	+0.245	.004	7	view →
KICH	Male	II,III,IV	−0.092	.019	4	view →
HNSC	Male	IV	+0.086	.027	3	view →
ESCA	All	II,III,IV	+0.330	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

CYCSP28–STAD

Open the STAD breakdown →