CYCSP22

Across TCGA patient cohorts, CYCSP22 RNA expression is significantly associated with the protein abundance of many other proteins, with 3,661 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CYCSP22-associated proteins across cancer lineages are SIK2_S343, BRD3, and BTF3. Each is linked with CYCSP22 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYCSP22-to-partner and partner-to-CYCSP22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYCSP22 versus SIK2_S343 in GBM, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYCSP22→partner) and Y-score (partner→CYCSP22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SIK2_S343 →	-0.568	-1.342	<.001	<.001	3	2
GBM	BRD3 →	+0.189	+0.867	.007	.001	3	2
GBM	BTF3 →	+0.232	+1.226	.004	.003	3	2
GBM	EXOC1 →	+0.137	+0.930	<.001	.002	3	2
GBM	JRK_S457 →	+0.435	+1.379	<.001	<.001	3	2
PDAC	MAP2_S1353 →	+1.005	+0.373	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,661 associations by consensus.

CYCSP22 vs SIK2_S343 — GBM

Explore this scatter interactively →