CYCSP22

Across TCGA patient cohorts, CYCSP22 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,166 significant associations in total. LGG shows the largest number of these associations.

The most reproducible CYCSP22-associated GO terms across cancer lineages are Uterus morphogenesis, Cellular pigmentation, and Positive regulation of protein polyubiquitination. Each is linked with CYCSP22 in more than 3 cancer types. Because this analysis shows association rather than direction, both CYCSP22-to-partner and partner-to-CYCSP22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Uterus morphogenesis grouped by CYCSP22-low versus CYCSP22-high in SKCM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYCSP22→partner) and Y-score (partner→CYCSP22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Uterus morphogenesis →	+0.065	+0.016	.002	<.001	3	3
LAML	Cellular pigmentation →	+0.034	+0.055	.006	.007	2	4
STAD	Positive regulation of protein polyubiquitination →	+0.035	+0.036	<.001	.001	3	3
STAD	Positive regulation of rRNA processing →	+0.032	+0.069	.001	<.001	3	3
SKCM	Mammalian oogenesis stage →	+0.044	+0.013	.005	.003	3	3
STAD	rRNA 3'-end processing →	+0.040	+0.067	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,166 associations by consensus.

Uterus morphogenesis by CYCSP22 expression — SKCM

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