CYCSP2

Across TCGA patient cohorts, CYCSP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,453 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CYCSP2-associated GO terms across cancer lineages are Positive regulation of DNA repair, Regulation of DNA repair, and Positive regulation of DNA metabolic process. Each is linked with CYCSP2 in more than 15 cancer types. Because this analysis shows association rather than direction, both CYCSP2-to-partner and partner-to-CYCSP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by CYCSP2-low versus CYCSP2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYCSP2→partner) and Y-score (partner→CYCSP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA repair →	+0.045	+0.414	<.001	<.001	3	16
STAD	Regulation of DNA repair →	+0.047	+0.368	<.001	<.001	3	16
STAD	Positive regulation of DNA metabolic process →	+0.049	+0.381	<.001	<.001	3	15
STAD	Cellular response to light stimulus →	+0.045	+0.384	<.001	<.001	3	15
STAD	Peptidyl-lysine acetylation →	+0.054	+0.420	<.001	<.001	3	15
STAD	Regulation of RNA splicing →	+0.060	+0.400	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,453 associations by consensus.

Positive regulation of DNA repair by CYCSP2 expression — STAD

Explore this box plot interactively →