Across TCGA pan-cancer cohorts, CYCSP11 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated CYCSP11 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher CYCSP11 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CYCSP11 expression acts as an unfavorable survival marker, although some lineages such as OV and STAD show a favorable association.

OV, PAAD, and LGG are the cancer types where CYCSP11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Tertile	IV	0.537	0.279	.003	48	view →
PAAD	OS	Tertile	II,III,IV	0.296	0.569	.003	27	view →
LGG	OS	Tertile	All	0.155	0.470	<.001	27	view →
UVM	DFS	Tertile	All	0.079	0.746	<.001	27	view →
THCA	DFS	Tertile	All	0.085	0.811	.007	27	view →
STAD	OS	Median	III,IV	0.675	0.355	.003	24	view →
LUAD	DFS	Tertile	All	0.476	0.691	.002	18	view →
LUSC	DFS	Tertile	III,IV	0.480	0.671	.024	18	view →
GBM	DFS	Median	All	0.384	0.201	.011	15	view →
SKCM	DFS	Tertile	IV	0.036	0.433	<.001	9	view →
KICH	DFS	Tertile	III,IV	0.043	0.897	.045	9	view →
READ	OS	Tertile	IV	0.423	0.937	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

Exploration

Same gene, other analysis: CYCSP11 tumor-vs-normal RNA expression · all CYCSP11 data types