CYCSP10

Across TCGA pan-cancer cohorts, CYCSP10 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated CYCSP10 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher CYCSP10 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CYCSP10 expression acts as an unfavorable survival marker, although some lineages such as READ and UVM show a favorable association.

MESO, ACC, and KIRC are the cancer types where CYCSP10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Quartile	All	0.244	0.485	.002	78	view →
ACC	DFS	Median	All	0.341	0.761	<.001	65	view →
KIRC	DFS	Quartile	All	0.516	0.759	.002	60	view →
KICH	DFS	Median	III,IV	0.373	1.000	.008	59	view →
READ	OS	Median	All	0.798	0.480	<.001	55	view →
LGG	DFS	Median	All	0.642	0.824	<.001	54	view →
UVM	OS	Median	All	0.736	0.469	.005	53	view →
BRCA	OS	Median	II,III,IV	0.974	0.940	.002	48	view →
HNSC	DFS	Quartile	IV	0.774	0.540	<.001	37	view →
SKCM	OS	Quartile	II,III,IV	0.551	0.200	<.001	31	view →
LIHC	DFS	Quartile	All	0.395	0.592	.001	23	view →
CESC	DFS	Quartile	All	0.738	0.897	.002	20	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

CYCSP10–MESO (DFS)

Open the MESO breakdown →