CYCSP1

Across TCGA patient cohorts, CYCSP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 5,897 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CYCSP1-associated proteins across cancer lineages are NAV1_S490, PAFAH2, and NASP_T390. Each is linked with CYCSP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYCSP1-to-partner and partner-to-CYCSP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYCSP1 versus NAV1_S490 in LUAD, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYCSP1→partner) and Y-score (partner→CYCSP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NAV1_S490 →	+0.712	+0.294	<.001	<.001	3	2
LUAD	PAFAH2 →	-0.206	-0.326	.002	<.001	3	2
HNSC	NASP_T390 →	-0.431	-0.515	.003	.006	3	2
GBM	P3H2 →	-0.706	-0.525	<.001	<.001	3	2
CCRCC	ARHGAP31_S863 →	+0.224	+0.272	.001	.004	3	2
CCRCC	POLA1_T219 →	-0.647	-0.478	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,897 associations by consensus.

CYCSP1 vs NAV1_S490 — LUAD

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