CYCS

Across TCGA cell cohorts, CYCS RNA expression is significantly associated with the RNA expression of many other genes, with 7,169 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible CYCS-associated genes across cancer lineages are NDUFA4, DDX56, and POLR1F. Each is linked with CYCS in more than 15 cancer types. Because this analysis shows association rather than direction, both CYCS-to-partner and partner-to-CYCS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYCS versus NDUFA4 in BLOOD_Myeloma, with a Pearson correlation of 0.70.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYCS→partner) and Y-score (partner→CYCS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	NDUFA4 →	+1.452	+1.393	<.001	<.001	3	16
OESOPHAGUS	DDX56 →	+0.944	+1.065	.001	<.001	3	16
BLOOD_Myeloma	POLR1F →	+1.045	+1.121	<.001	<.001	3	15
BLOOD_Lymphoma	MRPL32 →	+0.842	+0.984	<.001	.002	3	15
BLOOD_Myeloma	CBX3 →	+0.874	+1.053	<.001	<.001	3	15
KIDNEY	PSMA2 →	+1.018	+1.178	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,169 associations by consensus.

CYCS vs NDUFA4 — BLOOD_Myeloma

Explore this scatter interactively →