CYC1

Across TCGA patient cohorts, CYC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,174 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CYC1-associated proteins across cancer lineages are SCRIB, NOP16, and BOP1. Each is linked with CYC1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CYC1-to-partner and partner-to-CYC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYC1 versus SCRIB in OV, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYC1→partner) and Y-score (partner→CYC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SCRIB →	+0.402	+0.894	<.001	<.001	3	8
OV	NOP16 →	+0.442	+0.697	.001	.002	3	7
BRCA	BOP1 →	+0.481	+0.985	<.001	<.001	3	7
UCEC	CLUH →	+0.396	+1.063	<.001	.002	3	7
BRCA	GRPEL1 →	+0.456	+0.896	<.001	<.001	3	7
LSCC	MRPS22 →	+0.472	+0.616	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,174 associations by consensus.

CYC1 vs SCRIB — OV

Explore this scatter interactively →