CYC1

Across TCGA patient cohorts, CYC1 mutation is significantly associated with the RNA expression of many other genes, with 657 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYC1-associated genes across cancer lineages are SLC20A1P2, MIR7702, and ARF4P4. Each is linked with CYC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYC1-to-partner and partner-to-CYC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC20A1P2 grouped by CYC1-low versus CYC1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYC1→partner) and Y-score (partner→CYC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLC20A1P2 →	+0.024	+3.123	.009	.006	3	2
UCEC	MIR7702 →	+0.245	+4.360	<.001	.004	3	2
HNSC	ARF4P4 →	+0.203	+5.182	<.001	.007	3	2
STAD	RNA5SP261 →	+0.493	+4.611	<.001	.001	3	2
STAD	MRPL57P6 →	+0.143	+3.929	.008	.005	3	2
STAD	RNU6-612P →	+0.502	+3.736	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 657 associations by consensus.

SLC20A1P2 by CYC1 expression — UCEC

Explore this box plot interactively →