CYC1

Across TCGA cell cohorts, CYC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,398 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CYC1-associated GO terms across cancer lineages are U4 snRNA 3'-end processing, Termination of RNA polymerase III transcription, and Positive regulation of chemotaxis. Each is linked with CYC1 in more than 13 cancer types. Because this analysis shows association rather than direction, both CYC1-to-partner and partner-to-CYC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, U4 snRNA 3'-end processing grouped by CYC1-low versus CYC1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYC1→partner) and Y-score (partner→CYC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	U4 snRNA 3'-end processing →	+0.133	+1.133	<.001	<.001	3	14
BONE	Termination of RNA polymerase III transcription →	+0.099	+0.979	.005	.002	3	12
BONE	Positive regulation of chemotaxis →	-0.127	-1.319	.001	<.001	3	12
BLOOD_Leukemia	Central nervous system morphogenesis →	-0.387	-0.650	<.001	<.001	3	11
BONE	P-body assembly →	+0.125	+1.143	<.001	<.001	3	11
BONE	Mitochondrial ribosome assembly →	+0.084	+0.858	<.001	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,398 associations by consensus.

U4 snRNA 3'-end processing by CYC1 expression — URINARY_TRACT

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