Across TCGA patient cohorts, CYB5RL mutation is significantly associated with the RNA expression of many other genes, with 101 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CYB5RL-associated genes across cancer lineages are MIR5708, ZNF519P4, and RNU4-45P. Each is linked with CYB5RL in more than 1 cancer types. Because this analysis shows association rather than direction, both CYB5RL-to-partner and partner-to-CYB5RL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5RL→partner) and Y-score (partner→CYB5RL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR5708 →	+0.268	+7.954	<.001	.008	3	2
UCEC	ZNF519P4 →	+0.386	+3.077	<.001	.009	3	2
SKCM	RNU4-45P →	+0.138	+4.810	<.001	.002	3	2
BLCA	ABCD1P5 →	+0.097	+5.106	<.001	.008	3	2
COAD	MIR7975 →	+0.525	+6.734	<.001	<.001	3	2
BRCA	MIR6853 →	+0.364	+9.057	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 101 associations by consensus.

Exploration

CYB5RL survival (RNA) · tumor vs normal (RNA) · all CYB5RL data types