CYB5R3

Across TCGA patient cohorts, CYB5R3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,982 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CYB5R3-associated proteins across cancer lineages are TRIOBP, PACSIN2, and VCL. Each is linked with CYB5R3 in more than 5 cancer types. Because this analysis shows association rather than direction, both CYB5R3-to-partner and partner-to-CYB5R3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYB5R3 versus TRIOBP in BRCA, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5R3→partner) and Y-score (partner→CYB5R3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TRIOBP →	+0.329	+0.412	<.001	<.001	3	6
OV	PACSIN2 →	+0.383	+0.778	<.001	<.001	3	6
UCEC	VCL →	+0.392	+0.362	.007	.003	3	6
OV	TLN2 →	+0.510	+0.654	<.001	.001	3	5
BRCA	POLD3_S307 →	-0.531	-0.421	<.001	.002	2	6
BRCA	SRPX →	+0.659	+0.457	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,982 associations by consensus.

CYB5R3 vs TRIOBP — BRCA

Explore this scatter interactively →