CYB5R3

Across TCGA cell cohorts, CYB5R3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,174 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CYB5R3-associated GO terms across cancer lineages are Regulation of Golgi inheritance, Caveola assembly, and COPI-coated vesicle budding. Each is linked with CYB5R3 in more than 16 cancer types. Because this analysis shows association rather than direction, both CYB5R3-to-partner and partner-to-CYB5R3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of Golgi inheritance grouped by CYB5R3-low versus CYB5R3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5R3→partner) and Y-score (partner→CYB5R3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of Golgi inheritance →	+0.198	+1.141	<.001	<.001	3	17
BONE	Caveola assembly →	+0.177	+0.958	<.001	<.001	2	17
LUNG_SCLC	COPI-coated vesicle budding →	+0.139	+1.098	<.001	<.001	3	16
LUNG_SCLC	Golgi transport vesicle coating →	+0.139	+1.098	<.001	<.001	3	16
LUNG_SCLC	COPI coating of Golgi vesicle →	+0.139	+1.098	<.001	<.001	3	16
BLOOD_Lymphoma	Protein import into peroxisome membrane →	+0.125	+0.842	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,174 associations by consensus.

Regulation of Golgi inheritance by CYB5R3 expression — UPPER_AERODIGESTIVE_TRACT

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