CYB5D2

Across TCGA patient cohorts, CYB5D2 protein abundance is significantly associated with the RNA expression of many other genes, with 671 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CYB5D2-associated genes across cancer lineages are GRK3, APOBEC3H, and GIPR. Each is linked with CYB5D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CYB5D2-to-partner and partner-to-CYB5D2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYB5D2 versus GRK3 in GBM, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5D2→partner) and Y-score (partner→CYB5D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GRK3 →	-0.406	-0.362	.001	.002	3	1
GBM	APOBEC3H →	-0.544	-0.572	<.001	.001	3	1
GBM	GIPR →	-0.459	-0.407	.006	.007	3	1
GBM	CD37 →	-0.543	-0.473	.003	<.001	3	1
GBM	SLC1A5 →	-1.215	-0.538	.003	.003	3	1
GBM	PTN →	+0.820	+0.376	.008	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 671 associations by consensus.

CYB5D2 vs GRK3 — GBM

Explore this scatter interactively →