CYB5D2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CYB5D2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,275 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CYB5D2-associated GO terms across cancer lineages are Eosinophil activation, Eosinophil degranulation, and Monocarboxylic acid catabolic process. Each is linked with CYB5D2 in more than 10 cancer types. Because this analysis shows association rather than direction, both CYB5D2-to-partner and partner-to-CYB5D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Eosinophil activation grouped by CYB5D2-low versus CYB5D2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5D2→partner) and Y-score (partner→CYB5D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTEosinophil activation →+0.171+0.989.001<.001311
URINARY_TRACTEosinophil degranulation →+0.171+0.989.001<.001311
UPPER_AERODIGESTIVE_TRACTMonocarboxylic acid catabolic process →+0.082+1.295<.001<.001311
UPPER_AERODIGESTIVE_TRACTFatty acid catabolic process →+0.092+1.143<.001<.001311
URINARY_TRACTEosinophil activation involved in immune response →+0.171+0.989.001<.001311
UPPER_AERODIGESTIVE_TRACTGolgi to plasma membrane protein transport →+0.138+1.186<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,275 associations by consensus.

Eosinophil activation by CYB5D2 expression — URINARY_TRACT

Box plot of Eosinophil activation in CYB5D2-low vs CYB5D2-high samples in URINARY_TRACT.

Explore this box plot interactively →

Exploration