CYB5D1

Across TCGA cell cohorts, CYB5D1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,368 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CYB5D1-associated GO terms across cancer lineages are DNA topological change, IMP biosynthetic process, and DNA-templated transcription initiation. Each is linked with CYB5D1 in more than 13 cancer types. Because this analysis shows association rather than direction, both CYB5D1-to-partner and partner-to-CYB5D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA topological change grouped by CYB5D1-low versus CYB5D1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5D1→partner) and Y-score (partner→CYB5D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	DNA topological change →	+0.096	+0.595	.001	.004	3	14
URINARY_TRACT	IMP biosynthetic process →	+0.236	+1.102	<.001	.004	3	12
LARGE_INTESTINE	DNA-templated transcription initiation →	+0.074	+1.377	<.001	<.001	3	12
BLOOD_Leukemia	RNA-templated transcription →	+0.118	+0.693	.002	.001	3	12
LARGE_INTESTINE	Transcription initiation at RNA polymerase II promoter →	+0.065	+1.276	<.001	<.001	3	12
BONE	Positive regulation of anoikis →	+0.181	+0.948	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,368 associations by consensus.

DNA topological change by CYB5D1 expression — KIDNEY

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