CYB5AP5

Across TCGA pan-cancer cohorts, CYB5AP5 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated CYB5AP5 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CYB5AP5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CYB5AP5 expression acts as an unfavorable survival marker, although some lineages such as BRCA show a favorable association.

LUAD, LIHC, and STAD are the cancer types where CYB5AP5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.254	0.840	<.001	162	view →
LIHC	OS	Tertile	All	0.383	0.706	<.001	126	view →
STAD	DFS	Tertile	All	0.286	0.564	.002	54	view →
ESCA	DFS	Tertile	III,IV	0.037	0.450	<.001	18	view →
KIRP	OS	Tertile	All	0.215	0.770	.014	18	view →
ACC	OS	Tertile	II,III,IV	0.115	0.598	.012	18	view →
PCPG	DFS	Tertile	All	0.112	0.769	.021	18	view →
BRCA	OS	Tertile	II,III,IV	0.947	0.903	.045	9	view →
LUSC	DFS	Tertile	III,IV	0.137	0.707	.020	9	view →
LGG	DFS	Tertile	All	0.224	0.411	.027	9	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

CYB5AP5–LUAD (OS)

Open the LUAD breakdown →