CYB5A

Across TCGA patient cohorts, CYB5A protein abundance is significantly associated with the RNA expression of many other genes, with 213 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CYB5A-associated genes across cancer lineages are CACNA1I, NFATC2, and MAP1LC3A. Each is linked with CYB5A in more than 1 cancer types. Because this analysis shows association rather than direction, both CYB5A-to-partner and partner-to-CYB5A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYB5A versus CACNA1I in PDAC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5A→partner) and Y-score (partner→CYB5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CACNA1I →	+0.354	+0.889	.005	.005	3	1
PDAC	NFATC2 →	+0.857	+1.210	.007	.004	3	1
PDAC	MAP1LC3A →	+0.727	+1.354	.004	.001	3	1
PDAC	CHRDL1 →	+2.225	+1.015	.001	.003	3	1
PDAC	RUBCNL →	+0.776	+1.342	.006	.002	3	1
PDAC	MEDAG →	+1.276	+0.890	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 213 associations by consensus.

CYB5A vs CACNA1I — PDAC

Explore this scatter interactively →