CYB5A

Across TCGA cell cohorts, CYB5A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,574 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CYB5A-associated GO terms across cancer lineages are Zymosterol metabolic process, Zymosterol biosynthetic process, and Cholesterol biosynthetic process. Each is linked with CYB5A in more than 5 cancer types. Because this analysis shows association rather than direction, both CYB5A-to-partner and partner-to-CYB5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zymosterol metabolic process grouped by CYB5A-low versus CYB5A-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB5A→partner) and Y-score (partner→CYB5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Zymosterol metabolic process →	+0.188	+1.237	<.001	.001	3	6
LUNG_NSCLC_LUAD	Zymosterol biosynthetic process →	+0.188	+1.237	<.001	.001	3	6
OVARY	Cholesterol biosynthetic process →	+0.185	+1.644	<.001	<.001	3	6
LARGE_INTESTINE	Positive regulation of sodium ion transport →	+0.137	+0.953	.004	.004	3	6
LUNG_NSCLC_LUAD	Secondary alcohol biosynthetic process →	+0.185	+1.358	<.001	<.001	3	6
LUNG_NSCLC_LUAD	Cholesterol biosynthetic process via desmosterol →	+0.174	+1.409	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,574 associations by consensus.

Zymosterol metabolic process by CYB5A expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →