CYB561A3

Across TCGA patient cohorts, CYB561A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,164 significant associations in total. OV shows the largest number of these associations.

The most reproducible CYB561A3-associated GO terms across cancer lineages are Positive regulation of autophagosome maturation, Interferon-mediated signaling pathway, and Amyloid-beta clearance by transcytosis. Each is linked with CYB561A3 in more than 26 cancer types. Because this analysis shows association rather than direction, both CYB561A3-to-partner and partner-to-CYB561A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of autophagosome maturation grouped by CYB561A3-low versus CYB561A3-high in OV.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB561A3→partner) and Y-score (partner→CYB561A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	Positive regulation of autophagosome maturation →	+0.055	+0.548	<.001	<.001	3	27
SCLC	Interferon-mediated signaling pathway →	+0.087	+0.458	<.001	.001	3	25
SCLC	Amyloid-beta clearance by transcytosis →	+0.121	+0.644	<.001	<.001	3	25
SCLC	Positive regulation of isotype switching to IgA isotypes →	+0.112	+0.536	<.001	.005	3	24
UCS	Negative regulation of peptidyl-tyrosine phosphorylation →	+0.056	+0.868	<.001	<.001	3	24
SCLC	Regulation of small GTPase mediated signal transduction →	+0.050	+0.755	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,164 associations by consensus.

Positive regulation of autophagosome maturation by CYB561A3 expression — OV

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