CYB561

Across TCGA patient cohorts, CYB561 protein abundance is significantly associated with the RNA expression of many other genes, with 5,196 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CYB561-associated genes across cancer lineages are SPDEF, ARMC3, and LRG1. Each is linked with CYB561 in more than 3 cancer types. Because this analysis shows association rather than direction, both CYB561-to-partner and partner-to-CYB561 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYB561 versus SPDEF in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYB561→partner) and Y-score (partner→CYB561) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPDEF →	+2.329	+0.449	<.001	<.001	3	4
UCEC	ARMC3 →	+1.226	+0.399	.001	<.001	3	3
HNSC	LRG1 →	+1.513	+0.554	<.001	<.001	3	3
LSCC	KIRREL1-IT1 →	-0.708	-0.293	.002	.009	3	3
UCEC	SMIM31 →	+1.316	+0.414	.001	.004	3	3
OV	SMIM22 →	+1.223	+0.612	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,196 associations by consensus.

CYB561 vs SPDEF — UCEC

Explore this scatter interactively →