Across TCGA cell cohorts, CXorf66 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CXorf66-associated genes across cancer lineages are NXPH2, GIMAP7, and ADH1A. Each is linked with CXorf66 in more than 1 cancer types. Because this analysis shows association rather than direction, both CXorf66-to-partner and partner-to-CXorf66 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXorf66→partner) and Y-score (partner→CXorf66) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	NXPH2 →	+0.041	+4.874	<.001	.002	3	1
SKIN	GIMAP7 →	+0.058	+4.196	<.001	.002	3	1
SKIN	ADH1A →	+0.053	+4.347	<.001	.001	3	1
BLOOD_Leukemia	TREH →	+0.022	+4.149	.001	.008	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

CXorf66 survival (RNA) · tumor vs normal (RNA) · all CXorf66 data types