CXXC4

Across TCGA cell cohorts, CXXC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,799 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CXXC4-associated GO terms across cancer lineages are Taxis, Vesicle coating, and Chemotaxis. Each is linked with CXXC4 in more than 9 cancer types. Because this analysis shows association rather than direction, both CXXC4-to-partner and partner-to-CXXC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Taxis grouped by CXXC4-low versus CXXC4-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CXXC4→partner) and Y-score (partner→CXXC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Taxis →	-0.085	-1.562	<.001	<.001	3	9
OESOPHAGUS	Vesicle coating →	+0.106	+0.510	.008	.007	2	10
SOFT_TISSUE	Chemotaxis →	-0.085	-1.562	<.001	<.001	3	9
SOFT_TISSUE	Zygotic specification of dorsal/ventral axis →	-0.222	-1.426	<.001	<.001	3	9
BONE	Cell-substrate adhesion →	-0.132	-0.736	.001	.005	3	9
SOFT_TISSUE	RNA surveillance →	+0.069	+1.035	.001	.003	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,799 associations by consensus.

Taxis by CXXC4 expression — SOFT_TISSUE

Explore this box plot interactively →