CXXC4

Across TCGA cell cohorts, CXXC4 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CXXC4-associated genes across cancer lineages are S100A7A. Each is linked with CXXC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CXXC4-to-partner and partner-to-CXXC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, S100A7A grouped by CXXC4-low versus CXXC4-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXXC4→partner) and Y-score (partner→CXXC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	S100A7A →	+0.021	+4.058	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

S100A7A by CXXC4 expression — BLOOD_Lymphoma

Explore this box plot interactively →