Across TCGA patient cohorts, CXXC1P1 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CXXC1P1-associated genes across cancer lineages are RN7SL470P, DUXAP3, and OR6C70. Each is linked with CXXC1P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CXXC1P1-to-partner and partner-to-CXXC1P1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXXC1P1→partner) and Y-score (partner→CXXC1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL470P →	+0.420	+4.279	.001	.008	3	1
UCEC	DUXAP3 →	+0.239	+4.525	.002	.005	3	1
UCEC	OR6C70 →	+0.084	+6.136	<.001	<.001	3	1
UCEC	RNU6-618P →	+0.580	+4.969	.001	.002	3	1
UCEC	RNU6-1155P →	+0.451	+7.060	<.001	<.001	3	1
UCEC	KRT17P4 →	+0.054	+4.326	.008	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

CXXC1P1 survival (RNA) · tumor vs normal (RNA) · all CXXC1P1 data types