CXCL9

Across TCGA patient cohorts, CXCL9 RNA expression is significantly associated with the mutation status of many other genes, with 13,690 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CXCL9-associated genes across cancer lineages are HSPG2, DIDO1, and VPS13C. Each is linked with CXCL9 in more than 5 cancer types. Because this analysis shows association rather than direction, both CXCL9-to-partner and partner-to-CXCL9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSPG2 grouped by CXCL9-low versus CXCL9-high in CESC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL9→partner) and Y-score (partner→CXCL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	HSPG2 →	+2.906	+1.647	.001	<.001	3	6
COAD	DIDO1 →	+2.643	+1.634	<.001	<.001	3	5
UCEC	VPS13C →	+2.584	+2.298	<.001	<.001	3	5
UCEC	KIAA1109 →	+2.075	+1.812	<.001	<.001	3	5
UCEC	OBSCN →	+1.505	+1.589	<.001	<.001	3	5
UCEC	AHNAK2 →	+1.624	+1.700	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,690 associations by consensus.

HSPG2 by CXCL9 expression — CESC

Explore this box plot interactively →