CXCL9

Across TCGA patient cohorts, CXCL9 protein abundance is significantly associated with the RNA expression of many other genes, with 4,930 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CXCL9-associated genes across cancer lineages are PDCD1, CD3E, and TRAV13-2. Each is linked with CXCL9 in more than 4 cancer types. Because this analysis shows association rather than direction, both CXCL9-to-partner and partner-to-CXCL9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CXCL9 versus PDCD1 in CCRCC, with a Pearson correlation of 0.86.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL9→partner) and Y-score (partner→CXCL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PDCD1 →	+1.668	+1.593	.009	.009	3	5
HNSC	CD3E →	+1.468	+1.740	<.001	<.001	3	5
CCRCC	TRAV13-2 →	+1.444	+1.681	<.001	.006	3	5
HNSC	TRAV17 →	+1.225	+1.874	<.001	<.001	3	5
HNSC	TRAJ17 →	+2.536	+1.697	<.001	<.001	3	5
HNSC	TRAJ9 →	+2.416	+1.804	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,930 associations by consensus.

CXCL9 vs PDCD1 — CCRCC

Explore this scatter interactively →