CXCL9

Across TCGA patient cohorts, CXCL9 mutation is significantly associated with the RNA expression of many other genes, with 99 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CXCL9-associated genes across cancer lineages are ETDB, MIR4648, and GC. Each is linked with CXCL9 in more than 1 cancer types. Because this analysis shows association rather than direction, both CXCL9-to-partner and partner-to-CXCL9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ETDB grouped by CXCL9-low versus CXCL9-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL9→partner) and Y-score (partner→CXCL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ETDB →	+0.049	+3.867	<.001	.002	3	2
UCEC	MIR4648 →	+1.463	+3.106	<.001	.007	3	2
SKCM	GC →	+0.512	+2.587	.002	.009	3	2
UCEC	LINC01706 →	+0.072	+4.206	.002	.001	3	2
LUSC	RNU7-70P →	+0.635	+4.748	<.001	.003	3	2
BLCA	RNU4-88P →	+0.378	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 99 associations by consensus.

ETDB by CXCL9 expression — SKCM

Explore this box plot interactively →