CXCL8

Across TCGA patient cohorts, CXCL8 RNA expression is significantly associated with the protein abundance of many other proteins, with 25,429 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CXCL8-associated proteins across cancer lineages are PRTN3, PADI4, and MMP8. Each is linked with CXCL8 in more than 9 cancer types. Because this analysis shows association rather than direction, both CXCL8-to-partner and partner-to-CXCL8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CXCL8 versus PRTN3 in BRCA, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL8→partner) and Y-score (partner→CXCL8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PRTN3 →	+1.494	+1.804	<.001	<.001	3	10
GBM	PADI4 →	+1.317	+2.478	<.001	<.001	3	10
GBM	MMP8 →	+1.455	+2.468	<.001	<.001	3	10
GBM	MMP9 →	+1.316	+2.210	<.001	<.001	3	10
GBM	MPO →	+1.325	+2.590	<.001	<.001	3	10
PDAC	BPI →	+1.571	+1.656	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,429 associations by consensus.

CXCL8 vs PRTN3 — BRCA

Explore this scatter interactively →