CXCL3

Across TCGA cell cohorts, CXCL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,263 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CXCL3-associated GO terms across cancer lineages are Regulation of cell adhesion molecule production, Positive regulation of protein deubiquitination, and Keratinocyte activation. Each is linked with CXCL3 in more than 14 cancer types. Because this analysis shows association rather than direction, both CXCL3-to-partner and partner-to-CXCL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell adhesion molecule production grouped by CXCL3-low versus CXCL3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL3→partner) and Y-score (partner→CXCL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of cell adhesion molecule production →	+1.192	+1.594	<.001	.001	3	15
PANCREAS	Positive regulation of protein deubiquitination →	+0.144	+2.496	.004	<.001	3	12
SOFT_TISSUE	Keratinocyte activation →	+1.226	+1.641	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of leukocyte migration →	+0.110	+2.200	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Negative regulation of cell adhesion molecule production →	+1.229	+1.766	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Chemotaxis →	+0.104	+2.578	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,263 associations by consensus.

Regulation of cell adhesion molecule production by CXCL3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →