CXCL2

Across TCGA patient cohorts, CXCL2 protein abundance is significantly associated with the protein abundance of many other proteins, with 933 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CXCL2-associated proteins across cancer lineages are BCOR_S488, AKAP12_S1395, and AHNAK_S5054. Each is linked with CXCL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CXCL2-to-partner and partner-to-CXCL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CXCL2 versus BCOR_S488 in LUAD, with a Pearson correlation of 0.64.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL2→partner) and Y-score (partner→CXCL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	BCOR_S488 →	+0.384	+0.725	<.001	.001	3	1
LUAD	AKAP12_S1395 →	+0.992	+0.862	.004	<.001	3	1
LSCC	AHNAK_S5054 →	+1.103	+1.001	<.001	<.001	3	1
LSCC	ARHGAP29_S1029 →	-0.891	-0.857	<.001	.001	3	1
LSCC	BBX_S183 →	-1.009	-0.946	.002	.002	3	1
LSCC	CAVIN2_S203 →	+0.791	+0.672	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 933 associations by consensus.

CXCL2 vs BCOR_S488 — LUAD

Explore this scatter interactively →