CXCL2

Across TCGA cell cohorts, CXCL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,894 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CXCL2-associated GO terms across cancer lineages are Regulation of cell adhesion molecule production, Cytoplasmic pattern recognition receptor signaling pathway, and Innate immune response-activating signaling pathway. Each is linked with CXCL2 in more than 12 cancer types. Because this analysis shows association rather than direction, both CXCL2-to-partner and partner-to-CXCL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell adhesion molecule production grouped by CXCL2-low versus CXCL2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL2→partner) and Y-score (partner→CXCL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of cell adhesion molecule production →	+1.345	+2.383	<.001	<.001	3	13
LIVER	Cytoplasmic pattern recognition receptor signaling pathway →	+0.087	+2.218	.005	.004	3	13
LUNG_NSCLC_LUSC	Innate immune response-activating signaling pathway →	+0.064	+1.844	.004	.002	3	13
LUNG_NSCLC_LUSC	Negative regulation of cell adhesion molecule production →	+1.346	+1.988	<.001	.001	3	13
LIVER	Response to manganese ion →	+0.123	+2.505	.001	.001	3	11
BLOOD_Leukemia	Skeletal myofibril assembly →	+0.571	+0.835	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,894 associations by consensus.

Regulation of cell adhesion molecule production by CXCL2 expression — BREAST

Explore this box plot interactively →