Across TCGA patient cohorts, CXCL17 protein abundance is significantly associated with the RNA expression of many other genes, with 8,485 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CXCL17-associated genes across cancer lineages are WFDC2, TTC6, and SCGB3A1. Each is linked with CXCL17 in more than 3 cancer types. Because this analysis shows association rather than direction, both CXCL17-to-partner and partner-to-CXCL17 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL17→partner) and Y-score (partner→CXCL17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	WFDC2 →	+2.447	+1.250	<.001	<.001	3	4
UCEC	TTC6 →	+1.208	+0.989	.003	<.001	3	4
HNSC	SCGB3A1 →	+4.405	+1.106	<.001	<.001	3	4
UCEC	PLEKHG7 →	+1.507	+1.252	<.001	.002	3	4
LSCC	CYP2B7P →	+2.242	+1.098	<.001	<.001	3	4
UCEC	CP →	+1.727	+1.482	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,485 associations by consensus.

Exploration

CXCL17 survival (RNA) · tumor vs normal (RNA) · all CXCL17 data types