Across TCGA cell cohorts, CXCL17 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,633 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CXCL17-associated GO terms across cancer lineages are Regulation of cytotoxic T cell degranulation, Negative regulation of cytotoxic T cell degranulation, and T cell mediated cytotoxicity. Each is linked with CXCL17 in more than 8 cancer types. Because this analysis shows association rather than direction, both CXCL17-to-partner and partner-to-CXCL17 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL17→partner) and Y-score (partner→CXCL17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of cytotoxic T cell degranulation →	+1.124	+1.097	<.001	<.001	3	9
URINARY_TRACT	Negative regulation of cytotoxic T cell degranulation →	+1.124	+1.097	<.001	<.001	3	9
LUNG_NSCLC_LUAD	T cell mediated cytotoxicity →	+0.270	+2.314	<.001	<.001	3	7
BREAST	Detection of cell density →	-0.070	-1.862	.007	.004	3	6
BREAST	Mucus secretion →	+0.327	+1.302	.003	.005	3	6
BREAST	Rab protein signal transduction →	+0.158	+2.610	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,633 associations by consensus.

Exploration

CXCL17 survival (RNA) · tumor vs normal (RNA) · all CXCL17 data types