CXCL16

Across TCGA patient cohorts, CXCL16 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,475 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CXCL16-associated proteins across cancer lineages are ARRB2, PFN1, and ICAM1. Each is linked with CXCL16 in more than 6 cancer types. Because this analysis shows association rather than direction, both CXCL16-to-partner and partner-to-CXCL16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CXCL16 versus ARRB2 in LSCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL16→partner) and Y-score (partner→CXCL16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARRB2 →	+0.372	+0.791	<.001	<.001	3	7
GBM	PFN1 →	+0.381	+0.653	<.001	<.001	3	7
BRCA	ICAM1 →	+0.837	+0.971	<.001	<.001	3	7
BRCA	IL4I1 →	+0.880	+0.857	<.001	<.001	3	7
GBM	RENBP →	+0.579	+0.588	<.001	<.001	3	6
GBM	SKAP2 →	+0.673	+0.723	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,475 associations by consensus.

CXCL16 vs ARRB2 — LSCC

Explore this scatter interactively →