CXCL16

Across TCGA patient cohorts, CXCL16 protein abundance is significantly associated with the RNA expression of many other genes, with 2,771 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CXCL16-associated genes across cancer lineages are ZBP1, IL21, and IKZF3. Each is linked with CXCL16 in more than 2 cancer types. Because this analysis shows association rather than direction, both CXCL16-to-partner and partner-to-CXCL16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CXCL16 versus ZBP1 in BRCA, with a Pearson correlation of -0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL16→partner) and Y-score (partner→CXCL16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZBP1 →	-0.639	-0.384	.005	.003	3	3
BRCA	IL21 →	-0.423	-0.660	.001	<.001	3	3
BRCA	IKZF3 →	-1.125	-0.612	<.001	.001	3	3
BRCA	ACADVL →	+0.481	+0.416	.003	.001	3	3
OV	OXNAD1 →	-0.397	-0.707	.006	.003	3	2
OV	METTL27 →	+1.271	+0.645	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,771 associations by consensus.

CXCL16 vs ZBP1 — BRCA

Explore this scatter interactively →