CXCL14

Across TCGA patient cohorts, CXCL14 protein abundance is significantly associated with the RNA expression of many other genes, with 16,541 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CXCL14-associated genes across cancer lineages are SLC25A48-AS1, SLC25A48, and COPZ2. Each is linked with CXCL14 in more than 7 cancer types. Because this analysis shows association rather than direction, both CXCL14-to-partner and partner-to-CXCL14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CXCL14 versus SLC25A48-AS1 in LSCC, with a Pearson correlation of 0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL14→partner) and Y-score (partner→CXCL14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SLC25A48-AS1 →	+1.407	+1.753	<.001	<.001	3	8
LSCC	SLC25A48 →	+0.780	+1.739	<.001	<.001	3	7
OV	COPZ2 →	+1.485	+1.310	<.001	<.001	3	6
UCEC	NKD1 →	+2.117	+1.008	<.001	<.001	3	5
COAD	SERP2 →	+0.947	+0.835	.004	.003	3	5
COAD	AXIN2 →	+1.248	+0.701	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,541 associations by consensus.

CXCL14 vs SLC25A48-AS1 — LSCC

Explore this scatter interactively →