CXCL14

Across TCGA patient cohorts, CXCL14 mutation is significantly associated with the RNA expression of many other genes, with 211 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CXCL14-associated genes across cancer lineages are DDX19B, ELP5, and KRT8. Each is linked with CXCL14 in more than 1 cancer types. Because this analysis shows association rather than direction, both CXCL14-to-partner and partner-to-CXCL14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DDX19B grouped by CXCL14-low versus CXCL14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL14→partner) and Y-score (partner→CXCL14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DDX19B →	+0.427	+3.225	.002	.009	3	1
UCEC	ELP5 →	+0.549	+3.491	.001	.002	3	1
UCEC	KRT8 →	+0.809	+3.491	.009	.002	3	1
UCEC	KRT78 →	+0.750	+3.459	<.001	.005	3	1
UCEC	MRM3 →	+0.531	+3.502	.002	.002	3	1
UCEC	RXFP4 →	+1.019	+3.470	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 211 associations by consensus.

DDX19B by CXCL14 expression — UCEC

Explore this box plot interactively →